Lorazepam

Esters []
Lorazepam acetate

Molecular structure via molpic
Conformer structure via 3Dmol.js
Molecular formula	C16H12Cl2N2O2
Molecular mass	335.2 g/mol
Predicted LogP	2.4
Melting point	206 °C
Chirality	racemic

Identifiers []
IUPAC name	7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
SMILES	CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)O)C3=CC=CC=C3Cl
InChI	InChI=1S/C16H12Cl2N2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3
InChIKey	FJIKWRGCXUCUIG-UHFFFAOYSA-N

Dosing
Elimination half-life	10–12 hours

Oral []
Threshold	0.3 - 0.5 mg
Light	0.5 - 1 mg
Common	1 - 2 mg
Strong	2 - 3 mg
Heavy	3 - 4 mg

Statistically derived dosages by Sernyl

Lorazepam

Lorazepam (also known as Lormetazepam, Methyllorazepam, N-Methyllorazepam, Loramet, Noctamid, Lormetazepamum, Chlorotemazepam, Ergocalm, Noctamide or WY-4082) is a substance of the benzodiazepine class.

Chemistry

Lorazepam is typically found in the form of its acetate ester.

Stereochemistry

Stereoisomers []
(+)-Lorazepam	(-)-Lorazepam

Legal status

• Brazil: Lorazepam is a B1 substance.
• Canada: Lorazepam is a Schedule IV substance.
• Germany: Lorazepam is a prescription only/Anlage III substance.
• United States: Lorazepam is a Schedule IV substance.

See also

• Substituted benzodiazepines
• Bluedark

External links

• Lorazepam (Wikipedia)
• Lorazepam / (+)-Lorazepam / (-)-Lorazepam (Wikidata)
• Lorazepam (DrugBank)
• Lorazepam / (+)-Lorazepam / (-)-Lorazepam (PubChem)
• Lorazepam / (+)-Lorazepam / (-)-Lorazepam (ChEMBL)
• Lorazepam (ChEBI)
• Lorazepam / (+)-Lorazepam / (-)-Lorazepam (Common Chemistry)
• Lorazepam (HMDB)
• Lorazepam (KEGG)
• Lorazepam / (+)-Lorazepam / (-)-Lorazepam (UNII)
• Lorazepam / (+)-Lorazepam / (-)-Lorazepam (EPA DSSTox)