Amlodipine

Salts []
Amlodipine besylate

Amlodipine adipate

Amlodipine maleate

Amlodipine mesylate

Amlodipine malate

Esters []
Amlodipine benzoate

Molecular structure via molpic

Conformer structure via 3Dmol.js
Molecular formula	C₂₀H₂₅ClN₂O₅
Molecular mass	408.9 g/mol
Predicted LogP	3
Melting point	199-201
Decomposition	Hazardous decomposition products formed under fire conditions - Carbon oxides, nitrogen oxides (NOx), sulfur oxides, hydrogen chloride gas. /Amlodipine besylate/
Solubility	slightly soluble in water
Chirality	racemic

Identifiers []
IUPAC name	3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
SMILES	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
InChI	InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
InChIKey	HTIQEAQVCYTUBX-UHFFFAOYSA-N

Dosing
Elimination half-life	30–50 hours
Duration of action	At least 24 hours

Amlodipine

Amlodipine (also known as Amlocard, Amlodipino, Coroval, Lipinox, Amlodipinum, Amlodipine Free Base, 3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, HGP0904, UK-4834011 or HGP-0904)

Chemistry

Amlodipine is typically found in the form of its besylate, adipate, maleate, mesylate and malate salts or its benzoate ester.

Stereochemistry

(RS)-Amlodipine is a racemic mixture of the optical stereoisomers:

Stereoisomers []
(+)-Amlodipine	(-)-Amlodipine

Legal status

Australia: Amlodipine is a S4 substance.
Canada: Amlodipine is a prescription only substance.
United Kingdom: Amlodipine is a prescription only substance.
United States: Amlodipine is a prescription only substance.
European Union: Amlodipine is a prescription only substance.

Anodyne

Amlodipine

Chemistry

Stereochemistry

Legal status

See also

External links